1+ months

Post Doctoral Scholar

Lexington, KY 40507
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Posting Details

Job Title Post Doctoral Scholar
Requisition Number DU06061
Work Location Lexington, KY
Salary Range $50,004
Type of Position Other
Position Time Status Full-Time
Required Education

PhD or MD/PhD in an area relevant to pharmacology or neuroscience

Required Related Experience

Prior experience in AD, TBI, or related neurological disease research is also desirable.

Required License/Registration/Certification


Physical Requirements

May require long periods of sitting and/or standing. May require lifting up to 25lbs.


Primarily days but some nights and weekends may be required

Job Summary

A postdoctoral scientist position is available immediately at the University of Kentucky, Lexington KY. The position is in the Sanders-Brown Center on Aging, an established research center in aging and dementia where independent basic and clinical scientists work in a collaborative environment. The Center on Aging also includes the NIH-funded Alzheimers Disease Center that provides unique and outstanding resources to support innovative research (e.g. longitudinally followed and well-characterized clinical cohorts, neuroimaging, biomarkers, autopsy specimens). Our Center has recently completed the first tier in state-of-the-art upgrades in core equipment and facilities to enable access to multiphoton in vivo imaging, cell sorting, single-cell transcriptomics, high-speed confocal imaging, multiplex tissue spatial profiling, and mouse behavioral phenotyping, to name a few. Postdocs can also collaborate with a number of other centers at the university that facilitate neuroscience research, including the Spinal Cord and Brain Injury Research Center, the Magnetic Resonance Imaging and Spectroscopy Center, the Center for Clinical and Translational Science, and the Kentucky Neuroscience Institute.

The successful candidate will benefit from an experienced mentor, a stimulating and collaborative research environment, and an organized training plan to propel their future career goals. There are ample opportunities for scientific growth, career enhancement, and development into an independent investigator in academia, industry, or other career paths. Although the project is currently funded by NIH, an integral part of postdoctoral training is the process of preparing a research proposal and writing a fellowship application, so postdocs are encouraged to apply for external funding when possible. Postdocs will also be eligible for applying to our Centers T32 training program, which focuses on diseases of the aging brain. Moreover, postdocs from our lab have a consistent track record for obtaining NIH-funded F32 and K99/R00 awards, which provides recognition for both the fellow and the Center on Aging.

We seek a highly motivated, creative, and collaborative individual to work on mechanistic and translational research projects focused on the detrimental inflammatory and neurodegenerative responses that contribute to pathophysiology in a mouse model of comorbid Vascular Contributions to Cognitive Impairment and Dementia (VCID) and Alzheimers disease (AD). A component of this project will utilize a novel brain-penetrant small molecule as an anti-inflammatory strategy to combat inflammatory-related pathophysiology to determine optimal dosing and timing in the comorbid disease environment. Anticipated approaches to delineate comorbid pathophysiology response will include a multifaceted approach harnessing multiphoton vascular imaging in intact animals, flow cytometry and cell sorting for transcriptional profiling, as well as cognitive phenotyping.

Skills / Knowledge / Abilities

Must have excellent interpersonal, organizational, verbal and written communication skills, a solid publication record, and appropriate experience.

Does this position have supervisory responsibilities? No
Preferred Education/Experience

Preference will be given to individuals with experience in one of the following areas: inducible conditional knockout mouse models, mouse neuropathology and behavior, primary glia/neuron cell culture, gene expression profiling, pharmacological modulation of glia signaling pathways

Deadline to Apply
University Community of Inclusion

The University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus.

As an Equal Opportunity Employer, we strongly encourage veterans, individuals with disabilities, women, and all minorities to consider our employment opportunities.

Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.

Posted: 2019-10-15 Expires: 2020-03-20

Career Employment at UK

UK offers fulfilling careers in diverse fields supporting our teaching, research and health care missions. We also offer a compelling benefits package, including a generous retirement savings match and a supportive work environment distinguished by a respect for the unique work-life needs of every individual. Our culture of learning also provides tremendous support and resources for ongoing education, training and development. 

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Post Doctoral Scholar

University of Kentucky
Lexington, KY 40507

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